By Yang Xia
This detailed e-book describes the newest details within the primary realizing of the biophysics and biochemistry of articular cartilage utilizing the state of the art practices in NMR and MRI. this is often the 1st publication of its sort, written via physicists and chemists in this very important tissue, whose degradation contributes to osteoarthritis and similar joint ailments. Connecting the elemental technology with the scientific imaging functions, the specialists Editors offer an authoritative addition to the literature.
Ideal for practicing actual scientists and radiologists with an curiosity within the basic technology in addition to device brands and scientific researchers operating with articular cartilage
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Extra info for Biophysics and biochemistry of cartilage by nmr and mri
The superficial zone is relatively poor in proteoglycans, but rich in collagen fibers, which align along the articular surface. In the transitional zone, collagen fibers have a less ordered organization with increased distribution of proteoglycans. In the radial zone, proteoglycan has the highest concentration but more variable in its distribution around cells. In the pericellular matrix of each chondrocyte, the concentration of proteoglycan can be two-fold higher than that in the matrix distant from the cells.
N. Redman, R. Williams, G. P. Dowthwaite, S. F. Oldfield, C. W. ) synovium, becomes vascularized, but the center remains avascular. 146 In the rest of this section, any joint mentioned is a mature joint in an adult. 2 Topographic Distributions in the Knee The adult knee (tibiofemoral) joint is probably the most studied joint in osteoarthritis research, both because of the high incidence of osteoarthritis associated with this joint and because of its easy surgical access. 1, the knee joint is a complex mechanical organ, the smooth movement of which is supported and controlled by multiple structural components (femur, tibia, patella, ligaments, and tendons).
In general, viscoelasticity is theoretically modeled using a spring–dashpot system to represent the elastic (solid) and fluid (interstitial water) phases, respectively. 117–120 In 1980, Mow et al. developed a biphasic model from mixture theory, which assumed a porous-permeable solid component of the cartilage ECM and a viscous fluid. , which additionally allowed quantitative treatment of the FCD. 6). 6a) involves a step-like load applied to the tissue and a resultant time-dependent (transient) deformation.