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By Mario Francisco Juruena

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These genes were first classified as potential candidates for circadian photoreceptors; however, additional analyses showed that these genes have an independent light effect in the circadian system of mammals (Ohdo, 2007). These clock genes found in other transcription factors such as BMAL1, CLOCK, CRY1 and Cry2. All of these proteins, including Per1, Per2, and Per3 establish oscillation periods of approximately 24 hours. The CLOCK-BMAL1 heterodimer is a linked DNA sequence that stimulates the transcription of genes that regulate behavior and metabolism and maintain physiological states.

Other aspects that could influence the results are related to different treatment scheme, disease duration, the duration of changes in the photoperiod and the climate of the study sites, or other differences on the methodology such as design. 3. Circadian rhythms and mood disorders Biological rhythms can affect mood states; conversely, they may be affected by them and thus contribute to the manifestation of depressive symptoms. Additionally, symptoms may occur at different frequencies: daily, monthly, seasonally or annually.

2009). Issues of stigma for first responders accessing support for post traumatic stress. International Journal of Emergency Mental Health, Vol. 11, pp. 79-85, ISSN 1522-4821 Sarai, K. (1994). Masked depression. Nippon Rinsho, Vol. 52, pp. V. & Lecrubier, Y. (2003). Mini-International Neuropsychiatric Interview, Japanese edition, Translated from English by T. Otsubo; H. Miyaoka. & K. Kamijima. Seiwa Shoten, ISBN 4-7911-0410-2, Tokyo, Japan Silverstein, B. (1999). Gender differences in the prevalence of clinical depression: the role played by depression associated with somatic symptoms.

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