Download The Long and Short Non-coding RNAs in Cancer Biology by Erwei Song PDF

By Erwei Song

The booklet conveys a entire wisdom of lengthy and brief ncRNAs in melanoma law and their potentials as diagnostic biomarkers and healing ambitions. themes coated comprise the molecular mechanisms of assorted sessions of ncRNAs (with emphasis on lengthy non-coding RNAs and microRNAs) in melanoma, the sensible roles of ncRNAs in regulating diverse melanoma hallmarks (including proliferation, apoptosis, stem-cell houses, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and healing resistance), the position of ncRNAs in regulating melanoma signaling circuitry courses (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic precis of medical and preclinical reviews that overview the opportunity of ncRNA signatures for melanoma analysis and diagnosis and methods to supply brief ncRNAs as healing molecules for melanoma remedy. This publication may perhaps function a complete source for researchers, graduate scholars and oncologists in ncRNA and melanoma learn and aid drug improvement via settling on ncRNA goals.

Show description

Read Online or Download The Long and Short Non-coding RNAs in Cancer Biology PDF

Best molecular biology books

Computational Analysis of Biochemical Systems: A Practical Guide for Biochemists and Molecular Biologists

A real figuring out of genetic and metabolic functionality and layout is facilitated via mathematical and computational tools for examining biochemical platforms. This hands-on reference teaches biochemists and molecular biologists using glossy computational equipment for the research of advanced biomedical platforms requiring a modest mathematical heritage.

Biological Sequence Analysis Using the SeqAn C++ Library (Chapman & Hall CRC Mathematical & Computational Biology)

An Easy-to-Use study software for set of rules trying out and DevelopmentBefore the SeqAn venture, there has been basically a scarcity of accessible implementations in series research, even for traditional projects. Implementations of wanted algorithmic elements have been both unavailable or difficult to entry in third-party monolithic software program items.

Nutrients and Epigenetics

Explores the Newly came across hyperlink among meals and Epigenetics present examine means that food are greater than simply nutrition parts and that definite foodstuff can influence the expression of genes that bring about the improvement of persistent ailments. With contributions from specialists in either fields, foodstuff and Epigenetics examines the epigenetic phenomena and the interesting implications of vitamin in this principally uncharted box.

The Chemical Bond. Structure and Dynamics

This encouraged ebook through essentially the most influential scientists of our time--including six Nobel laureates--chronicles our rising knowing of the chemical bond in the course of the final 9 a long time and into the longer term. From Pauling's early paintings at the constitution of the chemical bond utilizing x-ray and electron diffraction to Zewail's paintings at the dynamics of the chemical bond utilizing femtosecond lasers, from Crick's molecular biology to Rich's molecular reputation, this ebook explores a wealthy culture of medical historical past and accomplishment.

Additional resources for The Long and Short Non-coding RNAs in Cancer Biology

Sample text

ENCODE project writes eulogy for junk DNA. Science. 2012;337:1159–61. 5. Britten RJ, Davidson EH. Gene regulation for higher cells: a theory. Science. 1969;165(891):349–57. 6. Brosnan CA, Voinnet O. The long and the short of noncoding RNAs. Curr Opin Cell Biol. 2009;21(3):416–25. 7. Gibb EA, Brown CJ, Lam WL. The functional role of long non-coding RNA in human carcinomas. Mol Cancer. 2011;10(1):38–55. 8. Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.

RNA Biol. 2011;8(3):404–14. 16. Brannan CI, Dees EC, Ingram RS, Tilghman SM. The product of the H19 gene may function as an RNA. Mol Cell Biol. 1990;10(1):28–36. 17. Brockdorff N, Ashworth A, Kay GF, McCabe VM, Norris DP, Cooper PJ, Swift S, Rastan S. The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell. 1992;71(3):515–26. 18. Brown CJ, Hendrich BD, Rupert JL, Lafrenière RG, Xing Y, Lawrence J, Willard HF. The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus.

49. Hutvágner G, McLachlan J, Pasquinelli AE, Bálint É, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science. 2001;293(5531):834–8. 50. Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 2001;15(20):2654–9. 51. Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference.

Download PDF sample

Rated 4.16 of 5 – based on 37 votes